Title: Convergence of coronary artery disease genes onto endothelial cell programs
Publication status: In press at Nature
Gavin R. Schnitzler1,2,5*, Helen Kang3,4,*, Shi Fang1,5, Ramcharan S. Angom6, Vivian S. Lee-Kim1,5, X. Rosa Ma3,4, Ronghao Zhou3,4, Tony Zeng3,4, Katherine Guo3,4, Martin S. Taylor15, Shamsudheen K. Vellarikkal1,5, Aurelie E. Barry1,5, Oscar Sias-Garcia1,5, Alex Bloemendal1,2, Glen Munson1, Philine Guckelberger1, Tung H. Nguyen1, Drew T. Bergman1,7, Stephen Hinshaw16, Nathan Cheng1, Brian Cleary1,8, Krishna Aragam1,9, Eric S. Lander1,10,11, Hilary K. Finucane1,12,13,14, Debabrata Mukhopadhyay6, Rajat M. Gupta1,2,5,†, Jesse M. Engreitz1,2,3,4,17†
1. Broad Institute of MIT and Harvard, Cambridge, MA
2. The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute, Cambridge, MA
3. Department of Genetics, Stanford University School of Medicine, Stanford, CA
4. BASE Initiative, Betty Irene Moore Children’s Heart Center, Lucile Packard Children’s Hospital, Stanford, CA
5. Divisions of Genetics and Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston MA
6. Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Jacksonville, FL
7. Geisel School of Medicine at Dartmouth, Hanover, NH
8. Faculty of Computing and Data Sciences, Departments of Biology and Biomedical Engineering, Biological Design Center, and Program in Bioinformatics, Boston University, Boston, MA
9. Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA
10. Department of Biology, MIT, Cambridge, MA
11. Department of Systems Biology, Harvard Medical School, Boston, MA
12. Department of Medicine, Massachusetts General Hospital, Boston, MA
13. Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA
14. Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA
15. Department of Pathology, Massachusetts General Hospital, and Harvard Medical School, Boston, MA
16. Department of Chemical and Systems Biology, ChEM-H, and Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA
17. Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA