Jul 10, 2024
Rotarod test
- 1Northwestern University, Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815
Protocol Citation: Chuyu Chen 2024. Rotarod test. protocols.io https://dx.doi.org/10.17504/protocols.io.eq2lywe3rvx9/v1
License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol and it's working
Created: July 10, 2024
Last Modified: July 10, 2024
Protocol Integer ID: 103171
Keywords: ASAPCRN
Funders Acknowledgement:
Aligning Science Across Parkinson's [ASAP-020600] through the Michael J. Fox Foundation for Parkinson's Research (MJFF)
Grant ID: ASAP-020600
Abstract
Motor learning was assessed with an accelerating rotarod.
The task was done using a rotarod apparatus (Panlab) equipped with a mouse rod (3 cm diameter) and set to 4–40 rpm acceleration over 300 seconds.
The task consisted of daily sessions (five trials per session; intertrial-interval = 15 s, max trial duration = 300 s)
Mice were placed on the accelerating rotarod. The time of mouse fell from the rod was recorded. The mean of 5 trials is used for the final analysis