1. Dissolve 100 ug of dye in 50 ul of sterile DMSO (2 mg/mL)
2. Dilute fibrils to 1mg/mL concentration in PBS containing 0.1M bicarbonate (total volume: 0.95 mL)
3. Add 50 ug of dissolved dye to each reaction tube
4. Incubate overnight in eppendorf tube (foil-wrapped) with continuous shaking
5. In the morning, spin down the dye-fibril solution at 10,000 g for 10 min at 10C
6. Transfer the supernatant and dissolve the pellet with 1 mL of PBS (repeat 5 times)