Oct 02, 2024

Public workspaceOutcomes of Total Hip Replacement in Septic Arthritis of the Native Hip Joint Amongst the Adult Population: A Systematic Review

DOI
dx.doi.org/10.17504/protocols.io.8epv5r415g1b/v1
  • Teddy Cheong1,
  • Surya Varma Selvakumar2,
  • Ryan Kwang Jin Goh2,
  • Ing How Moo1
  • 1Changi General Hospital;
  • 2Nanyang Technological University
Teddy Cheong
Icon indicating open access to content
QR code linking to this content
DOI: dx.doi.org/10.17504/protocols.io.8epv5r415g1b/v1
Protocol Citation: Teddy Cheong, Surya Varma Selvakumar, Ryan Kwang Jin Goh, Ing How Moo 2024. Outcomes of Total Hip Replacement in Septic Arthritis of the Native Hip Joint Amongst the Adult Population: A Systematic Review. protocols.io https://dx.doi.org/10.17504/protocols.io.8epv5r415g1b/v1
License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License,  which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol and it's working
Created: October 02, 2024
Last Modified: October 02, 2024
Protocol Integer ID: 108929
Keywords: Hip Arthroplasty, Native, Septic arthritis, Outcomes
Abstract
Background: Septic arthritis is a debilitating condition that results in joint destruction and irreversible loss of joint function. Surgical treatment options include arthroscopy, resection arthroplasty and total hip replacement (THR). There is existing literature on the treatment of septic arthritis of various joints including periprosthetic or native joints. However, to our knowledge, there is a lack of a consolidated review that focuses solely on THR outcomes in a previously infected native hip. This study aims to be the first systematic review that examines clinical outcomes of THR, specifically in septic arthritis of the native hip joint in the adult population.

Methodology: This systematic review will be conducted in accordance with relevant requirements of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement. PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature (CINAHL), SCOPUS, Cochrane Library, grey literature, and bibliographic references will be searched from inception to October 2023. Only case series or cohort studies published within the last 20 years assessing the outcomes of total hip replacement in native hip septic arthritis will be included. Literature retrieval and data extraction will be conducted by three independent reviewers. The overall methodological quality of the included studies will be assessed using the methodological index for non-randomized studies (MINORS) tool. Re-infection rate and various functional outcomes data such as the Harris Hip Score (HHS), Visual Analogue Scale (VAS), Merle D'Aubigne and Postel (MAP), Western Ontario, McMaster Universities Arthritis Index (WOMAC) Short Form 12-Item (SF-12) scores will be collected and analysed.

Expected Results: Expected to have 5-10 studies included after removal of duplicates and implementation of inclusion and exclusion criteria. Compiled results of re-infection rates and outcomes of THR in native septic arthritis of the hip will be reported and analysed.

Protocol references
Gupta MN, Sturrock RD, Field M. A prospective 2‐year study of 75 patients with adult‐onset septic arthritis. Rheumatology. 2001;40(1):24–30.
Balato G, Matteo VD, Ascione T, Giovanni RD, Marano E, Rizzo M, et al. Management of septic arthritis of the hip joint in adults. A systematic review of the literature. BMC Musculoskelet Disord. 2021;22:1006.
Hunter JG, Gross JM, Dahl JD, Amsdell SL, Gorczyca JT. Risk factors for failure of a single surgical debridement in adults with acute septic arthritis. J Bone Joint Surg Am. 2015;97(7):558-64.
Horowitz DL, Katzap E, Horowitz S, Barilla-Labarca ML. Approach to septic arthritis. Am Fam Physician. 2011;84(6):653-60.
Fleck EE, Spangehl MK, Rapuri VR, Beauchamp CP. An articulating antibiotic spacer controls infection and improves pain and function in a degenerative septic hip. Clin Orthop Relat Res. 2011;469(11):3055-64.
Girdlestone GR. Acute pyogenic arthritis of the hip: an operation giving free access and effective drainage. 1943. Clin Orthop Relat Res. 2008;466(2):258-63.
Bittar ES, Petty W. Girdlestone arthroplasty for infected total hip arthroplasty. Clin Orthop Relat Res. 1982;170:83–7.
McElwaine JP, Colville J. Excision arthroplasty for infected total hip replacements. J Bone Joint Surg Br. 1984;66(2):168-71.
D’Angelo FD, Monestier L, Zagra L. Active septic arthritis of the hip in adults: what’s new in the treatment? A systematic review. EFFORT Open Rev. 2021;6(3):164-172.
Slim K, Nini E, Forestier D, Kwiatkowski F, Panis Y, Chipponi J. Methodological index for non-randomized studies (minors): development and validation of a new instrument. ANZ J Surg. 2003;73(9):712-6.
Chen CE, Wang JW, Juhn RJ. Total hip arthroplasty for primary septic arthritis of the hip in adults. Int Orthop. 2008;32(5):573-80.
Dubin JA, Chen Z, Bains SS, Hameed D, Mont MA, Delanois RE et al. Less Than 1-Year Quiescent Period After Septic Arthritis of the Hip is Associated With High Risk of Periprosthetic Joint Infection Following Total Hip Arthroplasty. J Arthroplasty. 2022;38(5):930-934.
Huang TW, Huang KC, Lee PC, Tai CL, Hsieh PH. Encouraging outcomes of staged, uncemented arthroplasty with short-term antibiotic therapy for treatment of recalcitrant septic arthritis of the native hip. J Trauma. 2010;68(4):965-9.
Poignard A, Bouhou M, Homma Y, Hernigou P. Septic arthritis of the hip in adults with sickle cell anemia. Orthop Rev (Pavia). 2011;3(1):e1.
Ye X, Zeng J, Liu Y, Wang J. Clinical evaluation of total hip arthroplasty for osteoarthropathy secondary to septic hip arthritis. Medicine (Baltimore). 2023;102(11):e33227.
Anagnostakos K, Duchow L, Koch K. Two-stage protocol and spacer implantation in the treatment of destructive septic arthritis of the hip joint. Arch Orthop Trauma Surg. 2016;136(7):899-906.
Zeng WN, Liu JL, Jia XL, Zhou Q, Yang L, Zhang Y. Midterm Results of Total Hip Arthroplasty in Patients With High Hip Dislocation After Suppurative Hip Arthritis. J Arthroplasty. 2019;34(1):102-107.
Cho YJ, Patel D, Chun YS, Shin WJ, Rhyu KH. Novel Antibiotic-Loaded Cement Femoral Head Spacer for the Treatment of Advanced Pyogenic Arthritis in Adult Hip. J Arthroplasty. 2018;33(6):1899-1903.
Kelm J, Bohrer P, Schmitt E, Anagnostakos K. Treatment of proximal femur infections with antibiotic-loaded cement spacers. Int J Med Sci. 2009;6(5):258-264.
Russo A, Cavagnaro L, Chiarlone F, Clemente A, Romagnoli S, Burastero G. Clinical outcomes and survivorship of two-stage total hip or knee arthroplasty in septic arthritis: a retrospective analysis with a minimum five-year follow-up. Int Orthop. 2021;45(7):1683-1691.
Kao FC, Hsu YC, Liu PH, Tu YK, Jou IM. High 2-year mortality and recurrent infection rates after surgical treatment for primary septic arthritis of the hip in adult patients: An observational study. Medicine (Baltimore). 2019;98(32):e16765.
Papanna MC, Chebbout R, Buckley S, Stockley I, Hamer A. Infection and failure rates following total hip arthroplasty for septic arthritis: a case-controlled study. Hip Int. 2018;28(1):63-67.
Romano CL, Romano D, Meani E, Logoluso N, Drago L. Two-stage revision surgery with preformed spacers and cementless implants for septic hip arthritis: a prospective, non-randomized cohort study. BMC Infect Dis. 2011;11:129.
Zhang CF, Fang XY, Huang ZD, Bai GC, Zhuang ZY, Yang Y et al. Surgical Management for Chronic Destructive Septic Hip Arthritis: Debridement, Antibiotics, and Single‐Stage Replacement is as Effective as Two‐Stage Arthroplasty. Orthop Surg. 2022;14(6):1175-1185.
Tan TL, Xu C, Kuo FC, Ghanem E, George J, Shohat N et al. When Total Joint Arthroplasty After Septic Arthritis Can Be Safely Performed. JB JS Open Access. 2021;6(2):e20.00146.
Bauer T, Lacoste S, Lhotellier L, Mamoudy P, Lortat-Jacob A, Hardy P. Arthroplasty following a septic arthritis history: a 53 cases series. Orthop Traumatol Surg Res. 2010;96(8):840-3.
Luo H, He C, Zhao Y, Yang G, Hong H. Outcomes of single- vs two-stage primary joint arthroplasty for septic arthritis: a systematic review and meta-analysis. EFORT Open Rev. 2023;8(9):672-679.
Gomez MM, Tan TL, Manrique J, Deirmengian GK, Parvizi J. The Fate of Spacers in the Treatment of Periprosthetic Joint Infection. J Bone Joint Surg Am. 2015;97(18):1495-502.
Jung J, Schmid NV, Kelm J, Schmitt E, Anagnostakos K. Complications after spacer implantation in the treatment of hip joint infections. Int J Med Sci. 2009;6(5):265-73.
Aalirezaie A, Arumugam SS, Austin M, Bozinovski Z, Cichos KH, Fillingham Y et al. Hip and Knee Section, Prevention, Risk Mitigation: Proceedings of International Consensus on Orthopedic Infections. J Arthroplast. 2019;34(2S):S271-S278.
Ravn C, Neyt J, Benito N, Abreu MA, Achermann Y, Bozhkova S et al. Guideline for management of septic arthritis in native joints (SANJO). J Bone Jt Infect. 2023;8(1):29-37.
Couderc M, Bart G, Coiffier G, Godot S, Seror R, Ziza JM et al. 2020 French recommendations on the management of septic arthritis in an adult native joint. Joint Bone Spine. 2020;87(6):538-547.
Clinical guidelines for the antimicrobial treatment of bone and joint infections in Korea. Infect. Chemother. 2014;46:125–138.
Joo EJ, Kim B, Sohn KM, Kym S, Kim J. Administering Antibiotics for Less Than Four Weeks Increases the Risk of Relapse in Culture-Positive Septic Arthritis of Native Joints. J Clin Med. 2023;12(21):6808.