The donor is authorized for research by Lifeline of Ohio, Central Ohio’s organ procurement agency, 18-80 years of age, negative for HCV, HBV, HIV, and has no active COVID-19 infection. The whole heart is procured by Lifeline of Ohio and the biorepository then provides the de-identified heart to the researcher. When processing “normal” donor heart tissue, samples are chosen from the healthiest section of the five target regions of the heart: septum, left and right ventricles, and left and right atrium. The CT scans or chest X-rays are referenced to locate any diseased portions of these regions or to assess the overall health of the donor heart.
To be considered a “normal” donor heart, the donor has no known history of heart failure, no current infection, and limited inflammation.