Sep 28, 2024

Public workspaceNielsen and Ford (2024) - Reduced striatal M4-cholinergic signaling following dopamine loss differentially contributes to parkinsonian and L-DOPA-induced dyskinetic behaviors V.2

  • 1University of Colorado Anschutz Medical Campus
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Collection CitationBeatriz E Nielsen, Christopher P Ford 2024. Nielsen and Ford (2024) - Reduced striatal M4-cholinergic signaling following dopamine loss differentially contributes to parkinsonian and L-DOPA-induced dyskinetic behaviors. protocols.io https://dx.doi.org/10.17504/protocols.io.dm6gp336jvzp/v2Version created by Beatriz E Nielsen
License: This is an open access collection distributed under the terms of the Creative Commons Attribution License,  which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this collection and it's working
Created: August 23, 2023
Last Modified: September 28, 2024
Collection Integer ID: 104325
Keywords: ASAPCRN
Funders Acknowledgement:
NIH
Grant ID: R01-NS95809
NIH
Grant ID: R01-DA35821
Aligning Science Across Parkinson’s
Grant ID: ASAP-020529
Parkinson's Foundation
Grant ID: PF-PRF-839073
Abstract
This collection contains protocols detailing methods used in Nielsen and Ford (2024)-Reduced striatal M4-cholinergic signaling following dopamine loss differentially contributes to parkinsonian and L-DOPA-induced dyskinetic behaviors.

Files
Protocol
Icon representing the file Stereotaxic Surgery
Name
Stereotaxic Surgery
Version 1
, University of Colorado Anschutz Medical Campus
Beatriz E NielsenUniversity of Colorado Anschutz Medical Campus
Protocol
Icon representing the file Motor behavioral assessment
Name
Motor behavioral assessment
Version 1
, University of Colorado Anschutz Medical Campus
Beatriz E NielsenUniversity of Colorado Anschutz Medical Campus
Protocol
Icon representing the file Immunohistochemistry
Name
Immunohistochemistry
Version 1
, CU Anschutz
Kelsey BarcombCU Anschutz
Protocol
Icon representing the file 6-OHDA mouse model of Parkinson's disease
Name
6-OHDA mouse model of Parkinson's disease
Version 1
, University of Colorado Anschutz Medical Campus
Beatriz E NielsenUniversity of Colorado Anschutz Medical Campus
Protocol
Icon representing the file Levodopa-induced dyskinesia mouse model
Name
Levodopa-induced dyskinesia mouse model
Version 1
, University of Colorado Anschutz Medical Campus
Beatriz E NielsenUniversity of Colorado Anschutz Medical Campus
Protocol
Icon representing the file Electrophysiology and 2-photon imaging of Ca+2-transients
Name
Electrophysiology and 2-photon imaging of Ca+2-transients
Version 2
, University of Colorado Anschutz Medical Campus
Beatriz E NielsenUniversity of Colorado Anschutz Medical Campus
Protocol
Icon representing the file Ex vivo electrophysiology
Name
Ex vivo electrophysiology
Version 1
, University of Colorado Anschutz Medical Campus
Beatriz E NielsenUniversity of Colorado Anschutz Medical Campus
Protocol
Icon representing the file Western Blot
Name
Western Blot
Version 1
, University of Colorado Anschutz Medical Campus
Beatriz E NielsenUniversity of Colorado Anschutz Medical Campus
Protocol
Icon representing the file Acute Brain Slices
Name
Acute Brain Slices
Version 1
, CU Anschutz
Kelsey BarcombCU Anschutz