Apr 19, 2023
LEGACY01: DATA AND SAMPLE SHARING
- Katrina M Pollock1,
- Calliope Dendrou2
- 1NIHR Imperial Clinical Research Facility, ICTEM Building, Hammersmith Hospital Campus, Du Cane Road, London W12 0HS, UK;
- 2Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN
- Katrina M Pollock: Chief Investigator;
- Calliope Dendrou: Scientific Lead
Protocol Citation: Katrina M Pollock, Calliope Dendrou 2023. LEGACY01: DATA AND SAMPLE SHARING. protocols.io https://dx.doi.org/10.17504/protocols.io.81wgby4nqvpk/v1
License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol and it's working
Created: January 11, 2023
Last Modified: April 19, 2023
Protocol Integer ID: 75109
Keywords: Single-cell sequencing, lymph node, influenza vaccine, ancestry
Funders Acknowledgement:
Chan Zuckerberg Initiative
Grant ID: DAF2022-239944
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Abstract
This protocol details data and sample sharing in an experimental medicine study of seasonal influenza vaccination responses in Lymph nodE single-cell Genomics in AnCestrY (LEGACY01).
Attachments
602-1266.docx
631KB
Guidelines
DATA AND SAMPLE SHARING
The protocol will be published and made open access during the study.
During the study, data will be shared through controlled access using the following principles:
No data should be released that would compromise an ongoing trial or study.
There must be a strong scientific or other legitimate rationale for the data to be used for the requested purpose.
Investigators have a period of exclusivity in which to pursue their aims with the data before data are made available to other researchers.
Adequate resources must be available in order to comply in a timely manner or at all, and the scientific aims of the study must justify the use of such resources.
Data exchange complies with Information Governance and Data Security Policies in all the relevant countries.
Researchers wishing to access study data should contact the chief investigator in the first instance.
New algorithms or methods of value to the broader community will be shared online via the GitHub and/or protocols.io websites.
At the end of the study, single-cell data will be archived and made open access as part of the Human Cell Atlas data portal (https://data.humancellatlas.org/), and other data (e.g., imaging, bulk RNA sequencing, genotyping, flow cytometric, and serological data) will be made open access through deposition in the European Genome-phenome Archive (EGA; https//ega-archive.org), Cytobank (https://mrc.cytobank.org/cytobank/) and Zenodo (https://zenodo.org), for example. Meta-data deposited along with the sequencing data will be MINSEQE-compliant.