A structured, overarching, systematic approach to the body of evidence on the
effects of fasting in human health is lacking. This systematic overview of
literature aims to map the existing body of evidence, initiate a living
repository of evidence, and guide the development of a suite of specific
systematic reviews on the effects of fasting on human health. This protocol
describes the methods that will be used to conduct a systematic overview of the
literature on the effects of fasting on human health. The 2020 PRISMA Statement
provides reporting standards for the overview. We expect to develop a
high-level, narrative summary of the body of evidence related to fasting and
its effects on human health. The main limitations of the evidence included in
the overview will be discussed. Limitations of the review processes used in
this overview will also be addressed. High-level implications for practice,
policy, and future research will be described.