Mice (n = 20/experimental group) were randomly assigned to one of seven experimental conditions for each genotype:
1. 3 M Basal (no injections);
2. 6 M NaCl (NaCl injections started at 3 M);
3. 6 M LPS (LPS injections started at 3 M);
4.10 M NaCl (NaCl injections started at 7 M);
5.10 M LPS (injections started at 7M);
6. 16 M NaCl (injections started at 7 M);
7.16 M LPS (injections started at 7 M).