Wash the skull screw (s) / bolt (s) with 100% alcohol and air-dry them.
Drill a small craniotomy at the entry point of your interest; be sure to remove all bone fragments. Carefully clean the remainder of the skull surface and lightly score/scratch with a scalpel or drill to provide a key for the RelyX cement.
Drill small holes in the skull at a reasonable distance from craniotomy at the entry point of your interest and using a screwdriver insert 3 to 4 screws to anchor your implant. This step is an alternative but highly recommendable to get a long-lasting and stable recording.
Carefully lower the electrode tips to touch the brain surface. Observe each electrode while advancing to ensure a smooth advance without significant electrode bending or deviation.
When setting the initial implanted position, it is recommended that you implant the multi-electrode a few hundred microns above your target and then spend a couple of days slowly descending to the target. This approach is intended to reduce the chances of local tissue damage/micro-bleeding due to the relatively fast insertion employed during surgery compared to 50 microns per day descent after that.
Using the low-temperature cautery, carefully apply molten vaseline to the polyamide tube. Avoid pushing the drive and similarly avoid direct contact with the probe electrode when applying vaseline. The objective is to form a column of vaseline around the polyamide tube. Use the cautery to gently heat the vaseline so it runs down the polyamide tube to create the desired column. Excess vaseline can be easily removed with the spatula or cautery once cooled.
Apply the Relyx cement carefully to the Drive housing and vaseline column, making sure to run enough cement between the drive and the nearest clean skull surface. Use the curing light to set the cement as you work.
Take the loose end of the skull screw soldered to a wire for the ground. Carefully hold the loose end of the wire and solder it to the ground wire of the probe.
Carefully loosen the probe connector from the drive holder and position it to your desired location in the implant.
Cover the probe cables, loop them with cement, and build the cement up over the loop.