Feb 13, 2024
Catalepsy test in rats
- Eduard Bentea1,
- María Sanchiz Calvo1,
- Veerle Baekelandt1
- 1Katholieke Universiteit Leuven
Protocol Citation: Eduard Bentea, María Sanchiz Calvo, Veerle Baekelandt 2024. Catalepsy test in rats. protocols.io https://dx.doi.org/10.17504/protocols.io.q26g7p24kgwz/v1
License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol and it's working
Created: February 13, 2024
Last Modified: May 31, 2024
Protocol Integer ID: 95155
Keywords: ASAPCRN
Funders Acknowledgement:
ASAP (Aligning Science Across Parkinson's)
Abstract
Protocol for performing the catalepsy bar test in rats. This test evaluates muscular rigidity, and can be used in rat models with motor deficits, such as models of Parkison's disease.
Test
Test
1h
Bring cages to the behavioral room for at least 01:00:00 prior to the test for habituation
1h
Place both forepaws of the rat on an horizontal bar elevated so that the rat is in an half rearing position
Measure the descent latency, defined as the time it takes for both forepaws to be removed from the bar
Repeat the test three times, with a brief rest in between